Course Description: Implementation of NGS for TB – WHO Guidelines and Considerations

The Implementation of NGS for TB course provides a comprehensive overview of the World Health Organization (WHO) guidelines and recommendations for the use of next-generation sequencing (NGS) in tuberculosis (TB) diagnosis and drug resistance surveillance. Participants will explore how NGS is applied to identify resistant and susceptible Mycobacterium tuberculosis (MTB) strains and how it is endorsed by WHO for public health and clinical applications.

This course is designed for researchers, clinicians, and public health professionals who seek to understand the global framework for NGS implementation in TB control programs. It will equip participants with the knowledge needed to interpret WHO guidelines and apply them in laboratory and surveillance settings.

What You’ll Learn

• WHO Drug Resistance Catalogue: Understanding WHO-endorsed databases for interpreting TB drug resistance mutations.
• NGS for Resistant and Susceptible TB: How NGS is used to detect drug resistance and identify susceptible strains.
• WHO Guidelines and Recommendations: Summary of WHO documents on the use of NGS for TB diagnosis and surveillance.
• Public Health and Clinical Applications: How NGS is integrated into TB control programs and endorsed by the global community.
• Hands-On Training: Interpreting WHO’s catalogue of drug-resistant mutations and understanding its application in real-world settings.

By the end of this course, participants will be able to implement WHO-endorsed NGS approaches for TB drug resistance detection, ensuring effective and informed decision-making in TB management.